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Daptomycin Related Compounds & Impurities

Daptomycin is a cyclic lipopeptide antibiotic that inserts into bacterial membranes in a calcium-dependent manner to cause rapid membrane depolarisation and cell death, used for Gram-positive bacteraemia and right-sided endocarditis.

Simson Pharma Limited along with its subsidiary offices Simson Pharma Global Ltd. (UK) and Simson Pharma Global LLC (USA) is a trusted manufacturer and supplier of high-quality pharmaceutical reference standards, offering a comprehensive portfolio of Daptomycin reference standards, pharmacopeial and non-pharmacopeial Daptomycin impurities, related compounds, related substances, metabolites, stable isotope-labelled compounds, deuterium labelled compounds and nitrosamine (N-NO) reference standards.

These materials support pharmaceutical research and development, product development, ANDA and DMF submissions, quality control (QC), analytical method development and validation, stability studies, impurity identification, and genotoxic impurity assessment.

Our Daptomycin-related reference standards are thoroughly characterized using advanced analytical techniques and are supplied with comprehensive Certificates of Analysis (COA) and supporting analytical data from our USFDA certified, ISO 17025 and ISO 17034 accredited Lab, to meet global regulatory expectations. EP and USP traceable reference standards can also be provided upon request, subject to availability. Simson is also a provider of EP and USP traceable standards. To ensure consistent quality and reliability, our reference standards are periodically re-tested according to established quality management procedures.

Impurity Standards

2,2`-((3S,6S,15R,18R,21S,24S,30S,31R)-30-((S)-2-((R)-4-Amino-2-((S)-2-decanamido-3-(1H-indol-3-yl)propanamido)-4-oxobutanamido)-3-carboxypropanamido)-3-(2-(2-aminophenyl)-2-oxoethyl)-24-(3-aminopropyl)-6-((S)-1-carboxypropan-2-yl)-9-(hydroxymethyl)-18,31-dimethyl-2,5,8,11,14,17,20,23,26,29-decaoxo-1-oxa-4,7,10,13,16,19,22,25,28-nonaazacyclohentriacontane-15,21-diyl)diacetic Acid

CAT. No.D690012 CAS No.NA Mol. F.C72H101N17O26 Mol. W.1620.67 g/mol Stock Status Custom Synthesis
COA MSDS

Asp-cyclized Daptomycin

CAT. No.D690025 CAS No.NA Mol. F.C73H100N16O25 Mol. W.1601.70 g/mol Stock Status Custom Synthesis
COA MSDS

Daptomycin 11-glycine

CAT. No.D690046 CAS No.NA Mol. F.NA Mol. W.NA Stock Status Custom Synthesis
COA MSDS

Daptomycin 2-D-Alanine Analog

CAT. No.D690049 CAS No.2440130-58-3 Mol. F.C71H100N16O25 Mol. W.1577.65 g/mol Stock Status Custom Synthesis
COA MSDS

Daptomycin 6-L-lysine

CAT. No.D690045 CAS No.NA Mol. F.NA Mol. W.NA Stock Status Custom Synthesis
COA MSDS

Daptomycin 8-D-serine

CAT. No.D690044 CAS No.NA Mol. F.NA Mol. W.NA Stock Status Custom Synthesis
COA MSDS

Daptomycin 8-glycine

CAT. No.D690043 CAS No.NA Mol. F.NA Mol. W.NA Stock Status Custom Synthesis
COA MSDS

Daptomycin Anhydro Impurity

CAT. No.D690026 CAS No.121869-35-0 Mol. F.C72H99N17O25 Mol. W.1602.70 g/mol Stock Status Instock
COA MSDS

Daptomycin beta-Isomer

CAT. No.D690002 CAS No.123180-72-3 Mol. F.C72H101N17O26 Mol. W.1620.67 g/mol Stock Status Custom Synthesis
COA MSDS

Daptomycin Impurity 1

CAT. No.D690008 CAS No.NA Mol. F.C73H103N17O26 Mol. W.1634.70 g/mol Stock Status Custom Synthesis
COA MSDS

Daptomycin Impurity 10

CAT. No.D690034 CAS No.NA Mol. F.C73H103N17O27 Mol. W.1650.70 g/mol Stock Status Custom Synthesis
COA MSDS

Daptomycin Impurity 11

CAT. No.D690052 CAS No.NA Mol. F.C72H99N17O26 Mol. W.1618.65 g/mol Stock Status Custom Synthesis
COA MSDS

Daptomycin Impurity 12

CAT. No.D690051 CAS No.NA Mol. F.C73H103N17O26 Mol. W.1634.70 g/mol Stock Status Custom Synthesis
COA MSDS

Daptomycin Impurity 16

CAT. No.D690006 CAS No.NA Mol. F.C71H101N17O27 Mol. W.1624.66 g/mol Stock Status Custom Synthesis
COA MSDS

Daptomycin Impurity 17

CAT. No.D690019 CAS No.866822-35-7 Mol. F.C40H61N9O12 Mol. W.859.97 g/mol Stock Status Custom Synthesis
COA MSDS

Working Standards

Daptomycin

CAT. No.D690000 CAS No.103060-53-3  Mol. F.C72H101N17O26 Mol. W.1620.67 g/mol Stock Status Instock
COA MSDS

Isotope Labelled Compounds

Product structure

Sample structure

Catalogue no.: — CAS no.: — Formula: — Mol. weight: —

Illustrative sample structure
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