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Fosaprepitant Related Compounds & Impurities

Fosaprepitant is the phosphoryl prodrug of aprepitant, an NK1 receptor antagonist, administered intravenously for chemotherapy-induced nausea and vomiting prevention.

Simson Pharma Limited along with its subsidiary offices Simson Pharma Global Ltd. (UK) and Simson Pharma Global LLC (USA) is a trusted manufacturer and supplier of high-quality pharmaceutical reference standards, offering a comprehensive portfolio of Fosaprepitant reference standards, pharmacopeial and non-pharmacopeial Fosaprepitant impurities, related compounds, related substances, metabolites, stable isotope-labelled compounds, deuterium labelled compounds and nitrosamine (N-NO) reference standards.

These materials support pharmaceutical research and development, product development, ANDA and DMF submissions, quality control (QC), analytical method development and validation, stability studies, impurity identification, and genotoxic impurity assessment.

Our Fosaprepitant-related reference standards are thoroughly characterized using advanced analytical techniques and are supplied with comprehensive Certificates of Analysis (COA) and supporting analytical data from our USFDA certified, ISO 17025 and ISO 17034 accredited Lab, to meet global regulatory expectations. EP and USP traceable reference standards can also be provided upon request, subject to availability. Simson is also a provider of EP and USP traceable standards. To ensure consistent quality and reliability, our reference standards are periodically re-tested according to established quality management procedures.

Impurity Standards

Dibenzyl Phosaprepitant

CAT. No.F230006 CAS No.265121-01-5 Mol. F.C35H34F7N4O6P Mol. W.794.65 g/mol Stock Status Instock
COA MSDS

Dibenzyl Phosphate Impurity

CAT. No.F230010 CAS No.1623-08-1 Mol. F.C14H15O4P Mol. W.278.24 g/mol Stock Status Custom Synthesis
COA MSDS

Fosaprepitant (R,R,R)-Isomer

CAT. No.F230008 CAS No.1523569-90-5 Mol. F.C23H22F7N4O6P.2(C7H17NO5) Mol. W.1004.83 g/mol Stock Status Limited Stock
COA MSDS

Fosaprepitant Benzyl Ester

CAT. No.F230001 CAS No.889852-02-2 Mol. F.C30H28F7N4O6P Mol. W.704.54 g/mol Stock Status Instock
COA MSDS

Working Standards

Fosaprepitant

CAT. No.F230000A CAS No.172673-20-0 Mol. F.C23H22F7N4O6P Mol. W.614.41 g/mol Stock Status Custom Synthesis
COA MSDS

Fosaprepitant Dimeglumine

CAT. No.F230000 CAS No.265121-04-8 Mol. F.C23H22F7N4O6P.2(C7H17NO5) Mol. W.1004.83 g/mol Stock Status Instock
COA MSDS

Product structure

Sample structure

Catalogue no.: — CAS no.: — Formula: — Mol. weight: —

Illustrative sample structure
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