Lifitegrast Reference Standards & Impurities | Simson Pharma Private Limited

Lifitegrast Related Compounds & Impurities

Lifitegrast is a lymphocyte function-associated antigen-1 (LFA-1) antagonist ophthalmic solution used for dry eye disease.

Simson Pharma Limited along with its subsidiary offices Simson Pharma Global Ltd. (UK) and Simson Pharma Global LLC (USA) is a trusted manufacturer and supplier of high-quality pharmaceutical reference standards, offering a comprehensive portfolio of Lifitegrast reference standards, pharmacopeial and non-pharmacopeial Lifitegrast impurities, related compounds, related substances, metabolites, stable isotope-labelled compounds, deuterium labelled compounds and nitrosamine (N-NO) reference standards.

These materials support pharmaceutical research and development, product development, ANDA and DMF submissions, quality control (QC), analytical method development and validation, stability studies, impurity identification, and genotoxic impurity assessment.

Our Lifitegrast-related reference standards are thoroughly characterized using advanced analytical techniques and are supplied with comprehensive Certificates of Analysis (COA) and supporting analytical data from our USFDA certified, ISO 17025 and ISO 17034 accredited Lab, to meet global regulatory expectations. EP and USP traceable reference standards can also be provided upon request, subject to availability. Simson is also a provider of EP and USP traceable standards. To ensure consistent quality and reliability, our reference standards are periodically re-tested according to established quality management procedures.

Impurity Standards

(S)-2-((S)-2-(2-(benzofuran-6-carbonyl)5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid

CAT. No.L860030 CAS No.2641788-18-1 Mol. F.C39H35Cl2N3O10S2 Mol. W.840.75 g/mol Stock Status Instock

COA MSDS

(S)-2-(2-(benzofuran-6-carbonyl )-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-bromophenyl)propanoic acid

CAT. No.L860029 CAS No.NA Mol. F.C28H21BrCl2N2O5 Mol. W.616.29 g/mol Stock Status Instock

COA MSDS

(S)-2-(2-(benzofuran-6-carbonyl)-5, 7-dichloro-1,2-dihydroisoquinoline-6-carboxamido )-3-(3-(methylsulfonyl)phenyl)propanoic acid

CAT. No.L860027 CAS No.NA Mol. F.C29H22Cl2N2O7S Mol. W.613.47 g/mol Stock Status Custom Synthesis

COA MSDS

(S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1-oxo1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid

CAT. No.L860028 CAS No.NA Mol. F.C29H22Cl2N2O8S Mol. W.629.46 g/mol Stock Status Custom Synthesis

COA MSDS

(S)-2-(2-(benzofuran-6-carbonyl)-5-chloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid

CAT. No.L860025 CAS No.NA Mol. F.C29H25ClN2O7S Mol. W.581.04 g/mol Stock Status Custom Synthesis

COA MSDS

(S)-2-(2-(benzofuran-6-carbonyl)-7-chloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid

CAT. No.L860026 CAS No.NA Mol. F.C29H25ClN2O7S Mol. W.581.04 g/mol Stock Status Custom Synthesis

COA MSDS

(S)-2-amino-3-(3-(methylsulfonyl)phenyl)propanoic acid

CAT. No.L860040 CAS No.1270093-99-6 Mol. F.C10H13NO4S Mol. W.243.28 g/mol Stock Status Custom Synthesis

COA MSDS

(S)-methyl2-(5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoate hydrochloride

CAT. No.L860039 CAS No.NA Mol. F.C21H22Cl2N2O5S.HCl Mol. W.521.84 g/mol Stock Status Custom Synthesis

COA MSDS

Working Standards

Lifitegrast

CAT. No.L860000 CAS No.1025967-78-5 Mol. F.C29H24Cl2N2O7S Mol. W.615.48 g/mol Stock Status Instock

COA MSDS

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Lifitegrast Related Compounds & Impurities

Impurity Standards

(S)-2-((S)-2-(2-(benzofuran-6-carbonyl)5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid

(S)-2-(2-(benzofuran-6-carbonyl )-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-bromophenyl)propanoic acid

(S)-2-(2-(benzofuran-6-carbonyl)-5, 7-dichloro-1,2-dihydroisoquinoline-6-carboxamido )-3-(3-(methylsulfonyl)phenyl)propanoic acid

(S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1-oxo1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid

(S)-2-(2-(benzofuran-6-carbonyl)-5-chloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid

(S)-2-(2-(benzofuran-6-carbonyl)-7-chloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid

(S)-2-amino-3-(3-(methylsulfonyl)phenyl)propanoic acid

(S)-methyl2-(5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoate hydrochloride

2-(1-benzofuran-7-ylcarbonl)5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid

2-(tert-butoxycarbonyl)-5-chloro-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid

2-(tert-butoxycarbonyl)-7-chloro-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid

5,7-Dichloro-2-trityl-1,2,3,4-tetrahydro-isoquinoline-6-carboxylic acid

Benzyl (R)-2-amino-3-(3-(methylsulfonyl)phenyl)propanoate hydrochloride

Ethyl Benzofuran-6-carboxylate

Hydroxy Lifitegrast

Lifitegrast Ethyl Ester Impurity

Lifitegrast Hydroxy Impurity

Lifitegrast Impurity 1

Lifitegrast Impurity 1

Lifitegrast Impurity 10

Lifitegrast Impurity 11

Lifitegrast Impurity 12

Lifitegrast Impurity 13

Working Standards

Lifitegrast

Product structure

Sample structure